Clarity in Compliance.
Confidence in Quality.

We help medical device companies navigate complex regulatory, operational, and commercial challenges — with senior-led, multidisciplinary expertise at every step.

Schedule a Free Consultation
60+ Years Combined Experience
5 Core Disciplines
4 Practice Areas
100% Senior-Led Engagements

Our Services

Integrated expertise across the
full device lifecycle

Engage us for a single practice area or a bundled, multi-disciplinary solution — our four practice areas cover every stage from concept to commercialization.

Business Strategy

Navigate complex commercial landscapes with confidence — from M&A due diligence to market expansion.

  • Due diligence for M&A
  • Acquisition integration plans
  • Regulatory authority citation approach
  • Market expansion strategy
  • Portfolio & commercialization planning

Quality Management Systems

Build, audit, and strengthen your QMS to meet global regulatory requirements and drive continuous improvement.

  • ISO 9001/13485 design & implementation
  • FDA 21 CFR Part 820 / QMSR compliance
  • Internal & supplier audits
  • CAPA & root cause analysis
  • Post-market surveillance systems
  • FDA 483 & warning letter response
  • Adverse event remediation

Research & Development

De-risk your product development process with rigorous design controls and verification & validation.

  • Design history file (DHF) development
  • Device master & history records (DMR/DHR)
  • Risk management files (ISO 14971)
  • V&V planning & execution
  • Design controls implementation
  • FMEA & failure analysis

Scientific Affairs

Ground your submissions in rigorous science — from biocompatibility to cleaning & sterilization.

  • Biocompatibility assessments (ISO 10993)
  • Literature reviews & benefit-risk analyses
  • Cleaning & sterilization validation
  • Packaging & labeling compliance
  • Microbiological assessments

What We Provide

Comprehensive consulting services

The following represents a sample of methods we customize to fit your organization — from gap assessments through remediation and continuous improvement.

Quality Management & Compliance

  • QMS Implementation: Developing and implementing customized quality management systems aligned to your product and regulatory pathway.
  • Quality Audits: Internal and supplier audits to assess compliance and identify improvement opportunities.
  • CAPA Management: Establishing and managing corrective and preventive action programs with effective root cause analysis.
  • Gap Assessments: Structured evaluations against ISO 13485, FDA QSR/QMSR, and EU MDR requirements.
  • Inspection Readiness: FDA and notified body inspection preparation, support, and 483 response.
  • Post-Market Surveillance: Complaint handling, adverse event reporting, and post-market quality systems.
  • Quality Metrics: Developing and analyzing key quality indicators to drive improvement initiatives.

Research, Development & Design Controls

  • Design Controls: DHF, DMR, and DHR development and review across the product lifecycle.
  • Risk Management: Risk management files, hazard analysis, and ISO 14971 compliance.
  • Verification & Validation: V&V planning, protocol development, and execution support.
  • Design Reviews: Phase-appropriate design control and documentation oversight.
  • FMEA: Design and process failure mode and effects analysis.
  • Transfer & Scale-Up: Design transfer and manufacturing readiness support.

Scientific Affairs & Technical Assessments

  • Biocompatibility: ISO 10993 assessments and biological evaluation planning.
  • Cleaning Validation: Residue limits, cleaning process validation, and documentation.
  • Sterilization: Sterilization method selection, validation, and requalification support.
  • Packaging & Labeling: Packaging validation, shelf-life, and labeling compliance.
  • Literature Reviews: Benefit-risk analyses and scientific justification for submissions.
  • Microbiology: Microbiological assessments and environmental monitoring support.

Business Strategy & Remediation

  • M&A Due Diligence: Quality and regulatory assessments for acquisitions and divestitures.
  • Integration Planning: Post-acquisition QMS harmonization and integration roadmaps.
  • Regulatory Engagement: Strategy for regulatory authority citations and correspondence.
  • Market Expansion: Support entering new geographies and regulatory jurisdictions.
  • Remediation: Structured response to audit findings, warning letters, and compliance gaps.
  • Continuous Improvement: Process optimization and quality culture development.

Training & Workshop Programs

  • Regulatory & QMS Training: Customized on-site or virtual programs for your team.
  • Internal Auditing: Auditor training and audit program development.
  • CAPA & Root Cause: Practical tools for effective investigation and closure.
  • Design Controls: Training on DHF requirements and design control best practices.
  • Supplier Quality: Supplier qualification, surveys, and oversight programs.

How We Work

Our engagement process

A straightforward, three-step process designed to get you the right expertise as quickly as possible.

01

Discovery & Scoping

We start by learning your business objectives, product stage, and regulatory landscape. We'll identify the right subject matter expertise for your engagement and define a clear scope of work.

02

Execution & Delivery

Your engagement is led directly by a senior consultant with deep domain expertise — with peer review on every deliverable. We work within your timelines and integrate with your existing team.

03

Ongoing Support

Post-engagement, we offer retainer options for ongoing advisory support and are always available for follow-up questions. Your success is our success.

Engagement Models

Flexible ways to work with us

Project-Based

Fixed-scope, fixed-fee engagements for defined deliverables like internal audits or biocompatibility assessments.

Retainer

Monthly advisory retainers for ongoing strategic support, with a minimum 6-month commitment.

Workshop & Training

On-site or virtual training programs on regulatory, quality, and scientific topics customized to your team.

Ready to get started?

Schedule a discovery call and see how we've helped medical device companies solve their most complex challenges.

Schedule a Free Consultation Or keep scrolling to explore our capabilities.

Why AMPL

How we compare

See how AMPL Quality Partners stacks up against other consulting options.

AMPL Quality Partners Solo Contractors
Senior-led engagements ✓ ✓
Full lifecycle coverage ✓ ✕
Multi-discipline team ✓ ✕
Agile & responsive ✓ ✓
Peer-reviewed deliverables ✓ ✕
Deep regulatory SME expertise ✓ ~
Boutique, dedicated attention ✓ ✓
Lower overhead & cost ✓ ✓

Areas of Expertise

Standards, regulations & frameworks

Deep experience across the regulatory and quality frameworks that govern medical devices, pharmaceuticals, and related industries.

ISO 13485 Medical devices — quality management systems for regulatory purposes
ISO 9001 Quality management systems — general requirements
21 CFR Part 820 FDA Quality System Regulation & QMSR
21 CFR Part 11 Electronic records and electronic signatures
EU MDR 2017/745 European Medical Device Regulation
EU IVDR 2017/746 In Vitro Diagnostic Regulation
ISO 14971 Application of risk management to medical devices
ISO 10993 Biological evaluation of medical devices
MDSAP Medical Device Single Audit Program
Design Controls DHF, DMR, DHR, and design transfer requirements
510(k) / PMA / De Novo FDA premarket submission pathways
CE / Conformity Assessment EU market access and technical documentation

Core disciplines we bring to every engagement

Regulations & Standards Compliance Quality Engineering Biocompatibility Cleaning & Sterilization Packaging & Labeling Research & Development Design Controls Verification & Validation Risk Management Scientific Affairs

Who We Serve

Tailored solutions for every stage

Seed – Series B

Start-ups

Building your first QMS? Preparing your initial FDA submission? We help early-stage companies establish regulatory and quality foundations.

  • Regulatory strategy
  • QMS build-out
  • R&D advisory
50–500 employees

Growth-Stage SMEs

Expanding product lines or entering new markets? We scale quality and compliance alongside your business.

  • EU MDR transition
  • Market access strategy
  • Clinical affairs
500+ employees

Large OEMs & CDMOs

Need specialized surge capacity or deep expertise in a niche area? Our consultants integrate with your teams.

  • Audit support
  • Project-based regulatory
  • Specialized assessments

Contact

Let's work together

Tell us about your challenges. We'll respond within one business day to schedule an introductory call with the right consultant for your needs.

Industries we serve

Medical Devices Pharmaceuticals Beauty & Cosmetics Healthcare Tech